5 research outputs found
Multi-wavelength Diagnostics of the Precursor and Main phases of an M1.8 Flare on 2011 April 22
We study the temporal, spatial and spectral evolution of the M1.8 flare,
which occurred in NOAA AR 11195 (S17E31) on 22 April 2011, and explore the
underlying physical processes during the precursors and their relation to the
main phase. The study of the source morphology using the composite images in
131 {\deg}A wavelength observed by the SDO/AIA and 6-14 keV revealed a
multiloop system that destabilized systematically during the precursor and main
phases. In contrast, HXR emission (20-50 keV) was absent during the precursor
phase, appearing only from the onset of the impulsive phase in the form of
foot-points of emitting loop/s. This study has also revealed the heated
loop-top prior to the loop emission, although no accompanying foot-point
sources were observed during the precursor phase. We estimate the flare plasma
parameters viz. T, EM, power-law index, and photon turn-over energy by forward
fitting RHESSI spectral observations. The energy released in the precursor
phase was thermal and constituted ~1 per cent of the total energy released
during the flare. The study of morphological evolution of the filament in
conjunction with synthesized T and EM maps has been carried out which reveals
(a) Partial filament eruption prior to the onset of the precursor emission, (b)
Heated dense plasma over the polarity inversion line and in the vicinity of the
slowly rising filament during the precursor phase. Based on the implications
from multi-wavelength observations, we propose a scheme to unify the energy
release during the precursor and main phase emissions in which, the precursor
phase emission has been originated via conduction front formed due to the
partial filament eruption. Next, the heated leftover S-shaped filament has
undergone slow rise and heating due to magnetic reconnection and finally
erupted to produce emission during the impulsive and gradual phases.Comment: 16 Pages, 11 Figures, Accepted for Publication in MNRAS Main Journa
ESCAPADE: Encryption-type-ransomeware: system call based pattern detection
Encryption-type ransomware has risen in prominence lately as the go-to malware for threat actors aiming to compromise Android devices. In this paper, we present a ransomware detection technique based on behaviours observed in the system calls performed by the malware. We identify and present some common high-level system call behavioural patterns targeted at encryption-type ransomware and evaluate these patterns. We further present our repeatable and extensible methodology for extracting the system call log and patterns
Risk Factors, Clinical Characteristics, and Prognosis of Acute Kidney Injury in Hospitalized COVID-19 Patients: A Retrospective Cohort Study
Background: Acute kidney injury (AKI) is a serious complication of COVID-19. Methods: Records of hospitalized adult patients with confirmed SARS-CoV-2 infection from 1 March to 31 May 2020 were retrospectively reviewed. Results: Of 283 patients, AKI occurred in 40.6%. From multivariate analyses, the risk factors of AKI in COVID-19 can be divided into: (1) demographics/co-morbidities (male, increasing age, diabetes, chronic kidney disease); (2) other organ involvements (transaminitis, elevated troponin I, ST segment/T wave change on electrocardiography); (3) elevated biomarkers (ferritin, lactate dehydrogenase); (4) possible bacterial co-infection (leukocytosis, elevated procalcitonin); (5) need for advanced oxygen delivery (non-invasive positive pressure ventilation, mechanical ventilation); and (6) other critical features (ICU admission, need for vasopressors, acute respiratory distress syndrome). Most AKIs were due to pre-renal (70.4%) and intrinsic (34.8%) causes. Renal replacement therapy was more common in intrinsic AKI. Both pre-renal (HR 3.2; 95% CI 1.7–5.9) and intrinsic AKI (HR 7.7; 95% CI 3.6–16.3) were associated with higher mortality. Male, stage 3 AKI, higher baseline and peak serum creatinine and blood urea nitrogen were prevalent in intrinsic AKI. Urine analysis and the fractional excretion of sodium and urea were not helpful in distinguishing intrinsic AKI from other causes. Conclusions: AKI is very common in COVID-19 and is associated with higher mortality. Characterization of AKI is warranted due to its diverse nature and clinical outcome
Clinical characteristics of hospitalised patients with COVID-19 and the impact on mortality: a single-network, retrospective cohort study from Pennsylvania state
Objective COVID-19 is a respiratory disease caused by SARS-CoV-2 with the highest burden in the USA. Data on clinical characteristics of patients with COVID-19 in US population are limited. Thus, we aim to determine the clinical characteristics and risk factors for in-hospital mortality from COVID-19.Design Retrospective observational study.Setting Single-network hospitals in Pennsylvania state.Participants Patients with confirmed SARS-CoV-2 infection who were hospitalised from 1 March to 31 May 2020.Primary and secondary outcome measures Primary outcome was in-hospital mortality. Secondary outcomes were complications, such as acute kidney injury (AKI) and acute respiratory distress syndrome (ARDS).Results Of 283 patients, 19.4% were non-survivors. The mean age of all patients was 64.1±15.9 years. 56.2% were male and 50.2% were white. Several factors were identified from our adjusted multivariate analyses to be associated with in-hospital mortality: increasing age (per 1-year increment; OR 1.07 (1.045 to 1.105)), hypoxia (oxygen saturation <95%; OR 4.630 (1.934 to 1.111)), opacity/infiltrate on imaging (OR 3.077 (1.276 to 7.407)), leucocytosis (white blood cell >10 109/µL; OR 2.732 (1.412 to 5.263)), ferritin >336 ng/mL (OR 4.016 (1.195 to 13.514)), lactate dehydrogenase >200 U/L (OR 7.752 (1.639 to 37.037)), procalcitonin >0.25 ng/mL (OR 2.404 (1.011 to 5.714)), troponin I >0.03 ng/mL (OR 2.242 (1.080 to 4.673)), need for advanced oxygen support other than simple nasal cannula (OR 4.608–13.889 (2.053 to 31.250)), intensive care unit admission/transfer (OR 13.699 (6.135 to 30.303)), renal replacement therapy (OR 21.277 (5.025 to 90.909)), need for vasopressor (OR 22.222 (9.434 to 52.632)), ARDS (OR 23.810 (10.204 to 55.556)), respiratory acidosis (OR 7.042 (2.915 to 16.949)), and AKI (OR 3.571 (1.715 to 7.407)). When critically ill patients were analysed independently, increasing Sequential Organ Failure Assessment score (OR 1.544 (1.168 to 2.039)), AKI (OR 2.128 (1.111 to 6.667)) and ARDS (OR 6.410 (2.237 to 18.182)) were predictive of in-hospital mortality.Conclusion We reported the characteristics of ethnically diverse, hospitalised patients with COVID-19 from Pennsylvania state